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Does acetaminophen alter the glucose readings of the FreeStyle Libre System?

The FreeStyle Libre system has no contraindications or warnings for acetaminophen use.

In vitro study was conducted to examine the effect of acetaminophen (Tylenol), on FreeStyle Libre Sensor glucose readings. However, the effect of this substance in vivo has not been studied and may differ.

The finding is as follow: Acetaminophen was tested at a concentration of 20 mg/dL (or 1.1 mmol/L) in glucose-containing solution (10 times the maximum of the therapeutic range for acetaminophen) and demonstrated minimal impact on reported Sensor glucose values.204

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